What is TB-500
TB-500 is a synthetic version of Thymosin Beta4, which is a 43 formed amino-acid protein that regulates actin polymerization. This protein is used to improve healing of acute injuries that has a slow rate in recuperation process. Another common use of TB-500 is its administration after a heart attack due to its ability to repair damaged heart tissue through activation of cardiac progenitor cells, which acts as a repair system for the body.
How does TB-500 work?
Thymosin Beta4 intervenes in the regulation of actin polymerization encoding an actin sequestering protein in eukaryotic cells. It has a high conservation of sequence and localization in tissues and circulating cells of the human body. Actin is a cell-building protein that plays important roles in muscle contraction, cell division and cytokinesis, vesicle movement and the maintenance of cell junctions and cell shape.
Results and benefits
Thymosin is involved in cell proliferation, migration and differentiation caused through a specific interaction with actin in the cell cytoskeleton (giving the cell shape and mechanical resistance to deformation). Thymosin can even increase cellular respiration that allows cells gain useful energy to fuel cellular activity.
Thymosin increases red blood cell count and oxygen delivery to the muscles. This has as a result the improvement of the energy used by the body, which is useful to reduce the feeling of weakness and lethargic status. This protein also promotes the growth of new blood cells from the existing vessels through a process called angiogenesis, giving as a result the growth in the organism and the wound healing.
This peptide speeds injury repair, increases joint mobility, and encourages tissue repair, which are the desired effects of injured high performance athletes who do not want to go through a long recovery period. This fact has caused the athlete’s abuse in the use of this peptide that falls into doping issues. This peptide is not allowed to be consumed during official sport competitions due its faculty to improve the sport performance while it increases the recovery of injuries; the Australian Football League has been involved in a scandal related to the use of Thymosin.
Bodybuilders can make use of this peptide to promote the increase of muscle growth, enhance endurance, strength and improve muscle tone (that helps to maintain muscle posture). These benefits can be accomplished in a better manner than in the use of anabolic steroids that can cause unwanted side effects. The importance of muscle endurance resides in the capability of athletes to increase their performance in activities performed for long periods.
People that have used this peptide have not reported remarkable side effects although this peptide is a synthetic protein that mimics the natural function of Thymosin beta-4. The natural function of this protein prevents damage in organs that can be caused for pharmaceuticals that accomplish similar effects.
The advisable dose of Thymosin is 2-5mg once a week for four weeks and then one dose a month to maintain desired benefits.