PT-141 for sale
Bremelanotide (PT-141) is a peptide drug developed by Palatin Technologies and it is mainly used as a treatment for female sexual dysfunction (FSD), male erectile dysfunction (ED), hemorrhagic shock and reperfusion injury.
How does bremelanotide work?
Bremelanotide increases sexual desire through the activation in brain of the MC4 receptor, which regulates the metabolism, the sexual behavior and the male erectile function. Its operating mechanism involves an action in the central nervous system rather than directly on the vascular system.
Initially Bremelanotide was conceived as a sunless tanning agent and had its origins from the melanotan II peptide hormone, which is a synthetic analogue of the naturally occurring melanocortin peptide hormone that is used to produce melanogeseis (the production of a pigment found in the skin, eyes and hair called melanin). Nevertheless, Bremelanotide has caused sexual arousal and spontaneous male erections during testing, which showed the potential of this peptide as an effective treatment of sexual dysfunction in both men and woman.
In men, this peptide is used as a treatment of erectile dysfunction (the inability to develop or maintain an erection of the penis during sexual activity). An erection is accomplished while blood enters and is retained in sponge-like bodies within the penis because of sexual arousal. Due to the brain is in charge of transmitting signals to nerves in the penis, the stimulation of this process causes an erection through the use of Bremelanotide.
Bremelanotide is an effective treatment for arousal disorder, which is characterized by the lack or absence of desire for sexual activity in a situation that would normally produce a response to the stimulus. This disorder can be caused physically because of circulatory problems or alterations in neurological functions where low levels of libido (desire for sexual activity) are observed. Libido is regulated both by the sex hormones and the associated neurotransmitter that act upon testosterone and dopamine.
PT-141 side effects
A main side effect caused by nasal application of pt-141 was related to the increase of blood pressure in some patients who have used it. Later some studies showed that this peptide seemed to circumvent the presence of blood pressure side effects through its subcutaneous application. Due to the increase of blood pressure as a side effect, Bremelanotide has been developed as a treatment for hemorrhagic shock. Minor side effects reported for this peptide include nausea, yawning, stretching, decreased appetite, flushing, sweating, somnolence, headache and dizziness among others.
Bremelanotide has shown potential effects to improve social cognition and behavior, what also promotes it as a treatment for autism, which is a disorder of brain development characterized by difficulties in social interaction, verbal and nonverbal communication, and repetitive behaviors. Autism also is closely related to intellectual disability, difficulties in motor coordination and attention, and physical health issues.
PT 141 Dosage
Subcutaneous injection of Bremelanotide (PT 141) has showed favorable results in treating sexual dysfunction with doses of 0.75, 1.25 and 1.75 mg. Nevertheless it is necessary that it is administered under the supervision and recommendation of a medical specialist.