What is Adipotide
FTPP (Adipotide) is a peptidomimetic (a small protein-like chain designed to mimic a peptide), transformed into an experimental proapoptotic drug used for cellular death. Its purpose is to contribute to the weight loss. This substance has shown favorable results in tests and its main feature is its property of rapid loss weight.
How does it work?
Adipotide is designed to target specific blood vessels, supplying adipose tissue with blood. This process causes a shrinking effect on vessels, which forces the fat cells to feed on those vessels. All this mechanism gives origin to an apoptosis, which is a process of programmed cell death of multicellular organisms. There are two receptors where Adipotide binds: ANXA2 and prohibitin; these are found in blood vessels and accomplish the function of supplying white adipose tissue.
Results and benefits
Due to the laidback lifestyle of people and the contemporary work modality, the need of practicing physical activity has decreased, this causes more people to become overweight and obese. Adipotide help people in reducing their weight in a few months. When Adipotide cuts off the blood supply to fat cells, this process causes the loss of a certain amount of body weight and at the same time an additional amount of belly fat mass loss.
It contains potentiating effects on insulin sensitivity, improving it drastically. It is reflected in a more efficient use of insulin on the body, which has a positive effect on reducing elevated blood glucose levels. This process maintains health and allows the use of the energy from the chemical nutrients that the body receives.
Some studies have shown that Adipotide causes metabolic syndrome symptoms that increase thirst and urination, develop fatigue (tiredness) and cause blurred vision. Those are effects related to this peptide and it is advisable to be aware of them.
However, studies have not shown transcendent adverse effects. Participants in the case study showed no symptoms of nausea or appetite loss.
But this drug can generate adverse effects on kidney; these effects are dose-dependent and those are reversible injuries. Some of these effects are shown as reactive/regenerative and reactive/regenerative lesions in this organ. The kidney plays three key roles in the human body: it regulates water (removing the water excess but retaining it at the right time), balances the body’s minerals (allowing the correct functionality of the body), and processes hormones (useful on the regulation of blood pressure). In these facts lays the importance of the kidney, as well as the possible effects that could affect its proper operation.
The optimal dose of 43 mg/kg has been used on monkeys which resulted in no side effects.