What is Follistatin 344
Follistatin 344 is a protein used in order to increase muscle mass through the suppression of myostatin. Scientists discovered it while they observed the porcine follicular fluid in the ovaries. This protein can be found in the skeletal muscle of humans and other mammals, containing carbohydrates attached to it. Follistatin 344 was the first autocrine glycoprotein supplement to become popular in search of increased tissue mass.
How does it work?
Myostatin is a substance that inhibits myogenesis, which is the process of formation of muscular tissue during the embryonic development. In simpler terms, Follistatin 344 inhibits the regulation and limitation of muscle growth. However, there could be some issues related to this manipulation because the excess of myostatin can cause chronic diseases in vital organs, tissues and the bone marrow. At the same time, Follistatin could cause negative effects on health and reproductive capabilities, by suppressing secretion of follicle hormone as well as the pituitary gland.
Results and benefits
Unlike other myostatin inhibitors, Follistatin is not required to be administered on a daily basis and it is gaining the attention of scientists because of its anti-degenerative effects, as an alternative to treat muscle disorders. Some tests done on mice have shown no significant effects on organs and reproductive capabilities. Follistatin has been considered a more secure and a healthier alternative in search of increasing mass as compared with the widely used anabolics.
Apparently, Follistatin increases the appetite of individuals who use it. There are reports of people who used to have a caloric intake around 4000 calories and subsequently increased their intake up to more than 6000 calories. This fact should be taken with caution because at a high caloric intake, fat can accumulate around the body which makes it necessary to get into an adequate exercise routine to compensate these increases.
The frequent use of Myostatin inhibitors prevent the strength and growth of tendons and ligaments, which can cause heart problems. However, stopping the use of these substances can resolve these issues. It is worth mentioning that excess of anything can cause negative effects. Insofar as it acts in moderation, there will be no harmful effects incurred from its use.
A study about Spinal Muscular Atrophy (SMA) has shown that an increased level of this protein can raise life expectancy due to the improved muscle mass of certain muscular groups. Another study has discovered that Follistatin plays an important role in Polycystic Ovary Syndrome (PCOS), which is a widely known as an infertility disease.
The muscle mass effects could last up to 3 months after the completion of the course and it will gradually decrease when the body has stopped receiving the usual doses.
Follistatin 344 dosage
Follistatin is recommended for research, but people who have tried it themselves typically take injection 100 mcg/day of dose via injections for 10 to 30 days. Ideally it can be taken every third day. People who have taken doses up to 200 mcg have not shown suffered from any adverse effects than the ones who have taken lower doses.